How and where to order Farxiga, Forxiga (Dapagliflozin) 5 mg, 10 mg tablets online:

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Indications and usage:

Farxiga and Forxiga (Dapagliflozin Propanediol Monohydrate) tablets for oral use is a sodium-glucose cotransporter 2 (SGLT2) inhibitor indicated in adults for:

Type 2 Diabetes Mellitus:

as an adjunct to diet and exercise to improve glycemic control.

to reduce the risk of hospitalization for heart failure in adults with type 2 diabetes mellitus and established cardiovascular disease or multiple cardiovascular risk factors.

Heart Failure:

to reduce the risk of cardiovascular death and hospitalization for heart failure in adults with heart failure with reduced ejection fraction (NYHA class II-IV).

Limitations of use:

Not for treatment of type 1 diabetes mellitus or diabetic ketoacidosis.


Dosage and administration:

Assess renal function before initiating and then as clinically indicated.

Type 2 Diabetes Mellitus:

To improve glycemic control the recommended starting dose is 5 mg once daily, taken in the morning. Increase dose to 10 mg once daily in patients tolerating 5 mg who require additional glycemic control.

To reduce the risk of hospitalization for heart failure in adults with type 2 diabetes mellitus and established cardiovascular disease or multiple cardiovascular risk factors, the recommended dose is 10 mg once daily.

Dapagliflozin is not recommended for glycemic control when the eGFR is less than 45 mL/min/1.73 m2.

Heart Failure:

The recommended dose of Farxiga tablets is 10 mg once daily.


Dosage forms and strengths:

Farxiga (Dapagliflozin Propanediol Monohydrate) tablets 5 mg and 10 mg.

Forxiga (Dapagliflozin Propanediol Monohydrate) tablets 5 mg and 10 mg.


Overdosage:

There were no reports of overdose of dapagliflozin during the clinical development program for Farxiga. In the event of an overdose, contact a local poison control center. It is also reasonable to employ supportive measures as dictated by the patient's clinical status. The removal of dapagliflozin by hemodialysis has not been studied.


Contraindications:

History of serious hypersensitivity reaction to Farxiga (Dapagliflozin).

Severe renal impairment (eGFR less than 30 mL/min/1.73 m2) in patients who are being treated for glycemic control without established cardiovascular disease or cardiovascular risk factors.

Patients on dialysis.


Warnings and precautions:

Volume depletion: before initiating Farxiga, assess volume status and renal function in the elderly, patients with renal impairment or low systolic blood pressure, and in patients on diuretics. Monitor for signs and symptoms during therapy.

Ketoacidosis in patients with diabetes mellitus: assess patients who present with signs and symptoms of metabolic acidosis for ketoacidosis regardless of blood glucose level. If suspected, discontinue Dapagliflozin, evaluate and treat promptly. Before initiating Farxiga, consider risk factors for ketoacidosis. Patients on Farxiga (Dapagliflozin) may require monitoring and temporary discontinuation of therapy in clinical situations known to predispose to ketoacidosis.

Urosepsis and pyelonephritis: evaluate for signs and symptoms of urinary tract infections and treat promptly, if indicated.

Hypoglycemia: consider a lower dose of insulin or the insulin secretagogue to reduce the risk of hypoglycemia when used in combination with Farxiga.

Necrotizing fasciitis of the perineum (Fournier's gangrene): serious, life-threatening cases have occurred in patients with diabetes, both females and males. Assess patients presenting with pain or tenderness, erythema, or swelling in the genital or perineal area, along with fever or malaise. If suspected, institute prompt treatment.

Genital mycotic infections: monitor and treat if indicated.


Side effects, adverse reactions:

The most common adverse reactions associated with dapagliflozin pills, 5% or greater incidence, were female genital mycotic infections, nasopharyngitis, and urinary tract infections.

To report suspected adverse reactions of Farxiga or Forxiga (Dapagliflozin) 5 mg, 10 mg tablets contact AstraZeneca pharmaceutical company or your local FDA.


Drug interactions:

Positive urine glucose test

Monitoring glycemic control with urine glucose tests is not recommended in patients taking SGLT2 inhibitors as SGLT2 inhibitors increase urinary glucose excretion and will lead to positive urine glucose tests. Use alternative methods to monitor glycemic control.

Interference with 1,5-anhydroglucitol (1,5-AG) assay

Monitoring glycemic control with 1,5-AG assay is not recommended as measurements of 1,5-AG are unreliable in assessing glycemic control in patients taking SGLT2 inhibitors. Use alternative methods to monitor glycemic control.


Use in specific populations:

Pregnancy: advise females of the potential risk to a fetus especially during the second and third trimesters.

Lactation: dapagliflozin (Farxiga, Forxiga) is not recommended when breastfeeding.

Geriatrics: higher incidence of adverse reactions related to hypotension.

Renal impairment: higher incidence of adverse reactions related to hypotension and renal function.


Where to buy dapagliflozin online:

To purchase Forxiga, Farxiga (Dapagliflozin) tablets from reliable online pharmacies and drugstores at low prices please use resources described above on this webpage.


Here is a list of popular medications containing dapagliflozin as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

Trade name of the drug	Pharmaceutical forms and doses	Companies
Edistride	Tablets, Film-Coated; Oral; Dapagliflozin Propanediol Monohydrate 5 mg, 10 mg	AstraZeneca Associated Drug Co. Bristol-Myers Squibb Dr. Esteve Laboratorios TAU Laboratorio Vistor
Farxiga	Tablets, Film-Coated; Oral; Dapagliflozin Propanediol Monohydrate 5 mg, 10 mg	AstraZeneca
Forxiga	Tablets, Film-Coated; Oral; Dapagliflozin Propanediol Monohydrate 5 mg, 10 mg	AstraZeneca Anugerah Pharmindo Lestari Associated Drug Co. Bristol-Myers Squibb DKSH Distribution Four Star Vistor Zuellig Pharma
Oxra	Tablets, Film-Coated; Oral; Dapagliflozin Propanediol Monohydrate 5 mg, 10 mg	Sun Pharmaceutical Industries